Search results for "Flacourtia indica"

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MYOCARDIAL POTENCY OF AQUEOUS EXTRACT OF HARUNGANA MADAGASCARIENSIS STEM BARK AGAINST ISOPROTERENOL-INDUCED MYOCARDIAL DAMAGE IN RATS

2018

Objectives: The present study was undertaken to evaluate the effects of Harungana madagascariensis on electrocardiographical, biochemical and histopathological changes in isoproterenol (ISO)-induced myocardial infarction in rats. Methods: Male Wistar albino rats were randomly divided and treated with the aqueous extract of Harungana madagascariensis stem bark (AEHM, 200 and 400 mg/kg per os), or normal saline or vitamin E for 7 days with concomitant administration of ISO (85 mg/kg, subcutaneously) on 8th and 9th days, at 24 h interval. Results: The ISO injections to the rats caused cardiac dysfunction evidenced by a marked (P<0.01) elevation in ST-segment, a reduction in R wave amplitude (P…

medicine.medical_treatmentCardiac marker01 natural sciencesLipid peroxidation03 medical and health scienceschemistry.chemical_compound0302 clinical medicineLactate dehydrogenasemedicineHarungana[CHIM]Chemical SciencesPotencyComputingMilieux_MISCELLANEOUSbiologyTraditional medicinebusiness.industryVitamin E[SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciencesMalondialdehydebiology.organism_classification030205 complementary & alternative medicine0104 chemical sciences3. Good health010404 medicinal & biomolecular chemistrychemistryFlacourtia indicabusinessUniversal Journal of Pharmaceutical Research
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